Vaccine protocols

Expert practitioners present a comprehensive approach to vaccine development, production, and assessment that can be adapted successfully to any vaccine. Recent advances in vaccine research include those in the areas of bacterial genomics, antigen-specific T Cell quantification, genetic manipulation of vaccine vectors, the harnessing of natural molecules concerned with the regulation of immune responses, and the burgeoning field of DNA vaccinology. This second edition has been thoroughly revised with new chapters on live viral vaccine vectors, attenuated bacterial vectors, immunomodulators, MHC-peptide tetrameric complexes and the identification of vaccine candidates by genomic analysis. Additionally, chapters from the first edition have been updated to accommodate state-of-the-art methods in molecular vaccinology, making this a valuable and relevant practical manual for all those seeking to produce improved or novel vaccines.