Novel angiogenic mechanisms

This volume illustrates the current lines of investigation of the angiogenic mechanisms based on contribution of circulating progenitor cells. The main themes that currently dominate this research field are: the origin of these cells, their tissue engraftment, their phenotypic modulation leading to the transformation into endothelial cells, etc. This volume is a key reference for angiogenesis researchers and students alike, in the fields of cardiovascular medicine, neoplastic disorders, wound management and tissue engineering, among others. Key Features: + Fresh data and concepts are presented to advance our understanding of basic angiogenic mechanisms. + Focuses entirely on an emerging paradigm able to supplement the old angiogenic mechanism, called the "sprouting" model, in accounting for all real-life situations. + Deals with the potential of progenitor cells to contribute to the maintenance and/or regeneration of tissues in an adult organism.