The NMDA receptor

the long version

The NMDA receptor, an important protein in the brain, is involved in physiological processes such as synaptic transmission and synaptic plasticity which may underlie learning and memory. Pathological changes involving the NMDA receptors probably contribute to the development of epilepsy, acute neuronal damage such as that resulting from a stroke, and chronic neuropathologies like those associated with Alzheimer's disease. There is considerable interest in the development of pharmacological agents active in NMDA receptors as new therapeutic agents. This new edition provides a fully revised account of the NMDA receptor. Each chapter has been prepared by a leading expert in the field and has been fully updated to cover recent developments in the molecular biology and pharmacology of the NMDA receptor.